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A graduate of Ecole Normale Supérieure (Paris), Jean-Louis Mergny completed his PhD on the roles of nucleic acids followed by post-doctoral position in Basel, Switzerland. In 2009, he moved to the Institut Européen de Chimie Biologie (IECB) in Bordeaux where he was later appointed director. At the end of his 10-year term at IECB in 2020, he moved on to continue his research projects at the LOB (*a joint research unit CNRS, École Polytechnique - Institut Polytechnique de Paris, Inserm) in the Paris. The Covid crisis incited him to reorient my research projects towards pathogens with the aim of developing new therapeutic approaches against viral infections. He was appointed Head of the Biology Department at the Institut Polytechnique de Paris in September 2021, and became Co-Head of the " Engineering for Health " Interdisciplinary Center (E4H* https://www.ip-paris.fr/en/research/interdisciplinary-centers/e4h) in 2022. Co-author of over 300 original articles, he has collected over 41,000 citations according to Google Scholar.